Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 9/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3779737 | 0.93 | ELANE (0.44) | CHRM2CHRM1ELANEALDH1A1LMNA | |
| SCHEMBL6757054 | 0.87 | CHRM2 (0.52) | CHRM2CHRM1ELANECFDALDH1A1 | |
| SCHEMBL6761854 | 0.84 | CHRM2 (0.42) | CHRM2CHRM1ALDH1A1ROCK2KMT2A | |
| SCHEMBL3772904 | 0.83 | ALOX15 (0.41) | CHRM2CHRM1ALDH1A1KMT2ALMNA | |
| SCHEMBL2167312 | 0.81 | CHRM2 (0.66) | CHRM2CHRM1ELANEALDH1A1LMNA | |
| SCHEMBL27523797 | 0.81 | CHRM2 (0.57) | CHRM2CHRM1ELANEPRKCAPRKCD | |
| SCHEMBL6539682 | 0.80 | CHRM2 (0.39) | CHRM2CHRM1ELANEALDH1A1KMT2A | |
| SCHEMBL6760480 | 0.78 | CHRM2 (0.51) | CHRM2CHRM1ELANEKMT2AHTT | |
| SCHEMBL2166559 | 0.77 | CHRM2 (0.66) | CHRM2CHRM1ELANELMNA | |
| SCHEMBL8096707 | 0.75 | LMNA (0.37) | CHRM2CHRM1KMT2AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186061-A1 | Novel derivatives of 3,3-diphenylpropylamines | SCHWARZ PHARMA AG | 2004-09-23 | — | — | US | claimed |
| US-8338478-B2 | Derivatives of 3,3-diphenylpropylamines | UCB PHARMA GMBH (DE) | 2012-12-25 | — | — | US | disclosed |
| US-20040186061-A1 | Novel derivatives of 3,3-diphenylpropylamines | SCHWARZ PHARMA AG | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186061-A1 | Novel derivatives of 3,3-diphenylpropylamines | ADRB3, ADRA1D, TNNC1 | CHRM2 136/4885CHRM1 227/4885ELANE 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.