Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5296610 | 0.80 | TSHR (0.44) | TSHRMAPK1CYP3A4GPR84ALDH1A1 | |
| SCHEMBL13969444 | 0.77 | ALDH1A1 (0.37) | TSHRPOLBALDH1A1HSD17B10KDM4E | |
| SCHEMBL8163908 | 0.77 | CYP3A4 (0.51) | TSHRPOLBMAPK1CYP3A4GPR84 | |
| SCHEMBL4771040 | 0.75 | PPM1B (0.37) | TSHRMAPK1GPR84ALDH1A1KDM4E | |
| SCHEMBL14369814 | 0.75 | GPR84 (0.31) | GPR84 | |
| SCHEMBL11422586 | 0.74 | GPR84 (0.36) | GPR84 | |
| SCHEMBL13784900 | 0.74 | GPR84 (0.35) | GPR84 | |
| SCHEMBL3780920 | 0.73 | TSHR (0.46) | TSHRPOLBMAPK1CYP3A4ALDH1A1 | |
| SCHEMBL472107 | 0.73 | TSHR (0.59) | TSHRPOLBMAPK1CYP3A4ALDH1A1 | |
| SCHEMBL251713 | 0.72 | ALDH1A1 (0.44) | TSHRMAPK1CYP3A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661149-A | Synergistic antimicrobial compositions containing 1-hydroxymethylpyrazole and a preservative | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1997-08-26 | — | — | US | claimed |
| EP-0706080-B1 | Thermal transfer printing of a reducing agent to a silver source contained in an image receiving layer | AGFA GEVAERT NV (BE) | 2001-03-07 | — | — | EP | disclosed |
| US-5558972-A | Thermal transfer printing of a reducing agent to a silver source contained in an image receiving layer | AGFA-GEVAERT (BE) | 1996-09-24 | — | — | US | disclosed |
| US-5547809-A | INCREASED IMAGE DENSITY AND IMPROVED STABILITY OF REDUCTOR DONOR ELEMENT | AGFA-GEVAERT, N.V. (BE) | 1996-08-20 | — | — | US | disclosed |
| EP-0706080-A1 | Thermal transfer printing of a reducing agent to a silver source contained in an image receiving layer | AGFA-GEVAERT N.V. (BE) | 1996-04-10 | — | — | EP | disclosed |
| EP-0683428-A1 | Thermal transfer imaging system based on the heat transfer of a reducing agent for reducing a silver source to metallic silver | AGFA-GEVAERT N.V. (BE) | 1995-11-22 | — | — | EP | disclosed |