SCHEMBL7758563

SCHEMBL7758563

O=C(CC(=O)c1ccsc1)Nc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.66
NPC1 O15118 4/20 0.54
RAB9A P51151 4/20 0.54
KMT2A Q03164 4/20 0.54
KCNK3 O14649 1/20 0.54
KCNK9 Q9NPC2 1/20 0.54
HSD11B1 P28845 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
ALDH1A1 P00352 1/20 0.50
EPHX2 P34913 1/20 0.50
KDM1A O60341 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
LCK P06239 1/20 0.47
FYN P06241 1/20 0.47
DAO P14920 1/20 0.47
MEN1 O00255 3/20 0.47
ELANE P08246 1/20 0.46
MAPT P10636 1/20 0.45
GPR52 Q9Y2T5 1/20 0.44
CES2 O00748 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22721312 0.81 HPGD (0.65) HPGDNPC1RAB9AKMT2AKCNK3
SCHEMBL11572863 0.81 RAB9A (0.71) HPGDNPC1RAB9AKMT2AL3MBTL1
SCHEMBL1098345 0.81 RAB9A (0.77) HPGDNPC1RAB9AKMT2AL3MBTL1
SCHEMBL6623847 0.80 HPGD (1.00) HPGDNPC1RAB9AKCNK3KCNK9
SCHEMBL14890950 0.79 RAB9A (0.74) HPGDNPC1RAB9AKMT2AL3MBTL1
SCHEMBL4343950 0.79 L3MBTL1 (0.72) HPGDNPC1RAB9AKMT2AL3MBTL1
SCHEMBL22721318 0.78 CES1 (0.62) HPGDNPC1RAB9AKMT2AKCNK3
SCHEMBL4336119 0.77 LCK (0.59) HPGDNPC1RAB9AKMT2AKCNK3
SCHEMBL11782142 0.77 KMT2A (0.83) HPGDNPC1RAB9AKMT2AL3MBTL1
SCHEMBL5163099 0.76 CES2 (0.50) HPGDNPC1RAB9AKMT2AKCNK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0751427-B1 Image-dye-forming couplers and photographic elements containing them EASTMAN KODAK CO (US) 2001-03-28 EP claimed
EP-0751427-A1 Image-dye-forming couplers and photographic elements containing them KODAK LIMITED (GB) 1997-01-02 EP claimed
EP-0751427-B1 Image-dye-forming couplers and photographic elements containing them EASTMAN KODAK CO (US) 2001-03-28 EP disclosed
US-5693458-A THIENYLCARBONYLACETANILIDE DERIVATIVES; CONTRAST; PHOTOSTABILITY; STORAGE AND WET STABILITY; EASTMAN KODAK COMPANY (US) 1997-12-02 US disclosed
EP-0751427-A1 Image-dye-forming couplers and photographic elements containing them KODAK LIMITED (GB) 1997-01-02 EP disclosed