Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594882 | 0.79 | AKR1C3 (0.50) | MEN1GAAKMT2AUSP2KEAP1 | |
| SCHEMBL8861243 | 0.79 | MEN1 (0.70) | MEN1GAAKMT2AUSP2KEAP1 | |
| SCHEMBL11152281 | 0.75 | CYP3A4 (0.51) | MEN1GAAKMT2AUSP2KEAP1 | |
| SCHEMBL9222898 | 0.75 | AKR1C3 (0.44) | MEN1GAAKMT2AUSP2KEAP1 | |
| SCHEMBL353943 | 0.74 | FASN (0.64) | MEN1GAAKMT2AUSP2KEAP1 | |
| SCHEMBL5692519 | 0.73 | ESR1 (0.54) | MEN1GAAKMT2AUSP2LMNA | |
| 2,4-Dihydroxybenzophenone SCHEMBL1699129 | 0.73 | MEN1 (1.00) | MEN1GAAKMT2AUSP2KEAP1 | |
| 2,4-Dihydroxybenzophenone SCHEMBL30201813 | 0.73 | MEN1 (1.00) | MEN1GAAKMT2AUSP2KEAP1 | |
| 2,4-Dihydroxybenzophenone SCHEMBL29351647 | 0.73 | MEN1 (1.00) | MEN1GAAKMT2AUSP2KEAP1 | |
| SCHEMBL2868140 | 0.73 | MEN1 (0.72) | MEN1GAAKMT2AUSP2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6241785-B1 | HOIR DYES | L'OREAL (FR) | 2001-06-05 | — | — | US | disclosed |
| EP-0949897-B1 | USE OF FLAVYLIUM TYPE COMPOUNDS NON-SUBSTITUTED IN POSITION 3 FOR DYEING KERATINOUS FIBRES AND COMPOSITIONS CONTAINING THEM | OREAL (FR) | 2001-05-23 | — | — | EP | disclosed |
| EP-0949897-A1 | USE OF FLAVYLIUM TYPE COMPOUNDS NON-SUBSTITUTED IN POSITION 3 FOR DYEING KERATINOUS FIBRES AND COMPOSITIONS CONTAINING THEM | L'OREAL (FR) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998027940-A1 | USE OF FLAVYLIUM TYPE COMPOUNDS NON-SUBSTITUTED IN POSITION 3 FOR DYEING KERATINOUS FIBRES AND COMPOSITIONS CONTAINING THEM | L'OREAL (FR) | 1998-07-02 | — | — | WO | disclosed |