SCHEMBL7758730

SCHEMBL7758730

CC(=O)N(CCCN(C)C)C(C)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 3/20 0.44
CHRM2 P08172 2/20 0.44
CHRM4 P08173 2/20 0.44
CHRM5 P08912 2/20 0.44
CHRM3 P20309 2/20 0.44
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
PAOX Q6QHF9 1/20 0.41
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.40
DNM1 Q05193 3/20 0.36
KDM4A O75164 6/20 0.35
KDM4C Q9H3R0 6/20 0.35
KDM5A P29375 1/20 0.35
KDM7A Q6ZMT4 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
CHRNB2 P17787 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8375320 0.83 CHRM1 (0.48) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL17211990 0.83 LMNA (0.41) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL303673 0.80 CHRM2 (0.39) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL15727671 0.80 DNM1 (0.38) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL11240727 0.79 CHRM1 (0.44) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL10883164 0.79 USP2 (0.56) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL318875 0.77 PAOX (0.36) ALDH1A1TSHRPAOXUSP2LMNA
SCHEMBL20390 0.76 CHRM1 (0.43) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL2123995 0.76 CA12 (0.46) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL28395359 0.76 CHRM2 (0.36) CHRM1CHRM2CHRM4CHRM5CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0856509-B1 Process for the preparation of diacylimides CLARIANT GMBH (DE) 2001-04-04 EP disclosed
US-6028192-A Process for the preparation of diacylimides CLARIANT GMBH (DE) 2000-02-22 US disclosed
EP-0856509-A2 Process for the preparation of diacylimides Clariant GmbH (DE) 1998-08-05 EP disclosed
EP-0523085-B1 PEROXY ACID BLEACH PRECURSORS AND DETERGENT COMPOSITIONS CONTAINING THEM PROCTER & GAMBLE (US) 1996-08-21 EP disclosed
EP-0523085-A4 1994-03-30 EP disclosed
EP-0523085-A1 PEROXY ACID BLEACH PRECURSORS AND DETERGENT COMPOSITIONS CONTAINING THEM. PROCTER & GAMBLE (US) 1993-01-20 EP disclosed
WO-1991015474-A1 PEROXY ACID BLEACH PRECURSORS AND DETERGENT COMPOSITIONS CONTAINING THEM THE PROCTER & GAMBLE COMPANY (US) 1991-10-17 WO disclosed