SCHEMBL775875

SCHEMBL775875

[O-][S+](c1ccccc1F)c1ccccc1F

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.43
NFE2L2 Q16236 6/20 0.36
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
TAAR1 Q96RJ0 3/20 0.32
GAA P10253 1/20 0.32
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31
PSIP1 O75475 1/20 0.30
AOC3 Q16853 1/20 0.30
IDO1 P14902 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777872 0.85 ACHE (0.37) ACHENFE2L2
SCHEMBL7937933 0.82 ACHE (0.34) ACHENFE2L2NPC1RAB9ASMN1; SMN2
SCHEMBL514390 0.81 ACHE (0.42) ACHENFE2L2CES2CES1TAAR1
SCHEMBL4127092 0.80 ACHE (0.37) ACHECES2CES1TAAR1GAA
SCHEMBL16269560 0.80 ACHE (0.39) ACHENFE2L2GAASMN1; SMN2
SCHEMBL3207396 0.79 ACHE (0.50) ACHENFE2L2CES2CES1TAAR1
SCHEMBL31005130 0.79 ACHE (0.50) ACHENFE2L2CES2CES1TAAR1
SCHEMBL777916 0.79 CES2 (0.38) CES2CES1
SCHEMBL2460604 0.79 ACHE (0.40) ACHENFE2L2CES2CES1TAAR1
SCHEMBL18195202 0.79 ACHE (0.40) ACHENFE2L2CES2CES1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132782-A1 METHOD AND COMPOSITIONS FOR TREATING, PREVENTING OR LIMITING THE OCCURRENCE OF VIRAL INFECTION GLOBAL BIOLIFE INC. 2023-05-04 US claimed
EP-4121040-A1 METHOD AND COMPOSITIONS FOR TREATING, PREVENTING OR LIMITING THE OCCURRENCE OF VIRAL INFECTION Global Biolife Inc. (US) 2023-01-25 EP claimed
WO-2021188520-A1 METHOD AND COMPOSITIONS FOR TREATING, PREVENTING OR LIMITING THE OCCURRENCE OF VIRAL INFECTION GLOBAL BIOLIFE INC. (US) 2021-09-23 WO claimed
US-8034838-B2 Composition and method for the treatment of neurological disorders GLOBAL BIOLIFE, INC. 2011-10-11 US claimed
US-20090298932-A1 COMPOSITION AND METHOD FOR THE TREATMENT OF NEUROLOGICAL DISORDERS GLOBAL BIOLIFE, INC. 2009-12-03 US claimed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-20230132782-A1 METHOD AND COMPOSITIONS FOR TREATING, PREVENTING OR LIMITING THE OCCURRENCE OF VIRAL INFECTION GLOBAL BIOLIFE INC. 2023-05-04 US disclosed
EP-4121040-A1 METHOD AND COMPOSITIONS FOR TREATING, PREVENTING OR LIMITING THE OCCURRENCE OF VIRAL INFECTION Global Biolife Inc. (US) 2023-01-25 EP disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
US-11283107-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-22 US disclosed
CN-108430613-B Zwitterionic sulfone polymer blend and hollow fiber membranes 思拓凡瑞典有限公司 2022-02-11 CN disclosed
WO-2021188520-A1 METHOD AND COMPOSITIONS FOR TREATING, PREVENTING OR LIMITING THE OCCURRENCE OF VIRAL INFECTION GLOBAL BIOLIFE INC. (US) 2021-09-23 WO disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
US-6054501-A CURABILITY; GLOSSINESS; CAN BE BLENDED WITH INKS, PAINTS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2000-04-25 US disclosed
EP-0844255-A1 PHOTOPOLYMERIZATION INITIATOR AND ACTINIC RADIATION-CURABLE COMPOSITION COMPRISING THE SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1998-05-27 EP disclosed
EP-0629613-B1 Novel onium salt, photopolymerization initiator, energy ray-curing composition containing the initiator, and cured product NIPPON KAYAKU KK (JP) 1997-10-15 EP disclosed
US-5534557-A COATINGS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1996-07-09 US disclosed
US-5502083-A SULFONIUM CATALYST NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1996-03-26 US disclosed
EP-0629613-A2 Novel onium salt, photopolymerization initiator, energy ray-curing composition containing the initiator, and cured product NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1994-12-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230132782-A1 METHOD AND COMPOSITIONS FOR TREATING, PREVENTING OR LIMITING THE OCCURRENCE OF VIRAL INFECTION ACE2, ACE, TMPRSS2 ACHE 280/4885NFE2L2 823/4885CES2 332/4885
US-20090298932-A1 COMPOSITION AND METHOD FOR THE TREATMENT OF NEUROLOGICAL DISORDERS BACE1, APP, BACE2 ACHE 8/4885NFE2L2 2262/4885CES2 1502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.