Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.47 |
| ▸ | UQCRB | P14927 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | BRS3 | P32247 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19512927 | 0.81 | HPGD (0.51) | SLC40A1ALDH1A1GLO1CYP3A4MAPT | |
| SCHEMBL7761716 | 0.79 | MAPT (0.53) | UQCRBCA1CA2CYP1A2CYP3A4 | |
| SCHEMBL8164647 | 0.78 | GLO1 (0.55) | SLC40A1ALDH1A1KDM4EGLO1CA1 | |
| SCHEMBL22928035 | 0.78 | UQCRB (0.44) | ALDH1A1UQCRBEGFRTNNI3KCA1 | |
| SCHEMBL22928037 | 0.78 | UQCRB (0.44) | ALDH1A1UQCRBEGFRTNNI3KCA1 | |
| SCHEMBL678551 | 0.78 | CA1 (0.65) | ALDH1A1UQCRBCA1CA2KMT2A | |
| SCHEMBL8366960 | 0.78 | MAPT (0.52) | SLC40A1GLO1MAPTMAPK1KMT2A | |
| SCHEMBL22928034 | 0.77 | UQCRB (0.45) | ALDH1A1UQCRBEGFRTNNI3KCA1 | |
| SCHEMBL22928151 | 0.76 | SLC40A1 (0.48) | SLC40A1ALDH1A1UQCRBEGFRTNNI3K | |
| SCHEMBL22928032 | 0.76 | UQCRB (0.44) | ALDH1A1UQCRBEGFRTNNI3KCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512006-B1 | Novel 3-position Nitrogen substituted 6,6- disubstituted-5, 6-dihydropyrones and related compounds possess antiviral properties | WARNER-LAMBERT COMPANY | 2003-01-28 | — | — | US | disclosed |