SCHEMBL7759449

SCHEMBL7759449

COc1ccccc1NC(=O)NF

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.66
POLB P06746 2/20 0.64
MAPT P10636 4/20 0.63
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
HTT P42858 1/20 0.63
SMN1; SMN2 Q16637 4/20 0.62
RAB9A P51151 3/20 0.62
NPC1 O15118 2/20 0.62
HPGD P15428 2/20 0.59
KDM4E B2RXH2 1/20 0.59
GAA P10253 1/20 0.59
HSD17B10 Q99714 1/20 0.59
LPAR1 Q92633 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31040567 0.89 POLB (0.77) ALDH1A1POLBMAPTMEN1KMT2A
SCHEMBL4554983 0.89 POLB (0.77) ALDH1A1POLBMAPTMEN1KMT2A
SCHEMBL13923626 0.84 SMN1; SMN2 (0.68) ALDH1A1POLBMAPTMEN1KMT2A
SCHEMBL9036508 0.82 ALDH1A1 (0.71) ALDH1A1POLBMAPTMEN1KMT2A
SCHEMBL23331399 0.82 ALDH1A1 (0.66) ALDH1A1POLBMAPTMEN1KMT2A
SCHEMBL6850954 0.81 ALDH1A1 (0.71) ALDH1A1POLBMAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL9004628 0.81 ALDH1A1 (0.69) ALDH1A1POLBMAPTMEN1KMT2A
SCHEMBL171580 0.79 KMT2A (0.70) ALDH1A1POLBMAPTMEN1KMT2A
SCHEMBL514089 0.79 KMT2A (0.68) ALDH1A1POLBMAPTMEN1KMT2A
SCHEMBL2093160 0.79 ALDH1A1 (0.62) ALDH1A1POLBMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US claimed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO disclosed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 ALDH1A1 3840/4885POLB 3874/4885MAPT 1882/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 ALDH1A1 3840/4885POLB 3874/4885MAPT 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.