SCHEMBL7759490

SCHEMBL7759490

CN(C)c1ccc2c(c1N)Cc1ccccc1-2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
HPGD P15428 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 2/20 0.43
LMNA P02545 1/20 0.43
PGR P06401 1/20 0.40
ACHE P22303 5/20 0.39
BCHE P06276 1/20 0.39
TSHR P16473 1/20 0.37
ATM Q13315 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CHEK1 O14757 1/20 0.37
NEK2 P51955 1/20 0.37
LIMK1 P53667 1/20 0.37
DYRK1A Q13627 1/20 0.37
CLK4 Q9HAZ1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6676649 0.83 PGR (0.42) PNMTNPC1RAB9AALDH1A1MAPT
SCHEMBL30341585 0.79 PNMT (0.49) PNMTNPC1RAB9AALDH1A1MAPT
SCHEMBL1509311 0.79 PNMT (0.49) PNMTNPC1RAB9AALDH1A1MAPT
Hydrochloric Acid SCHEMBL7195499 0.79 PGR (0.40) PNMTNPC1RAB9AALDH1A1MAPT
SCHEMBL24896110 0.77 PNMT (0.47) PNMTNPC1RAB9AALDH1A1MAPT
Hydrochloric Acid SCHEMBL2870709 0.77 PNMT (0.47) PNMTNPC1RAB9AALDH1A1MAPT
SCHEMBL87731 0.77 NPC1 (0.50) PNMTNPC1RAB9AALDH1A1MAPT
SCHEMBL30297457 0.77 NPC1 (0.50) PNMTNPC1RAB9AALDH1A1MAPT
SCHEMBL7195505 0.76 PGR (0.38) PNMTNPC1RAB9AALDH1A1MAPT
Hydrochloric Acid SCHEMBL7927086 0.75 PNMT (0.49) PNMTNPC1RAB9AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0667562-B1 Charge injection barrier for positive charging organic photoconductor HEWLETT PACKARD CO (US) 2001-03-21 EP claimed
US-5556730-A Charge injection barrier for positive charging organic photoconductor HEWLETT-PACKARD COMPANY (US) 1996-09-17 US disclosed
US-5476604-A Crosslinked binder of polyvinyl alcohol HEWLETT-PACKARD COMPANY (US) 1995-12-19 US disclosed