SCHEMBL6676649

SCHEMBL6676649

CN(C)c1ccc2c(c1N(C)C)Cc1ccccc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.42
PNMT P11086 1/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
ALDH1A1 P00352 3/20 0.39
TSHR P16473 1/20 0.39
ATM Q13315 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MAPT P10636 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
KDM4E B2RXH2 3/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
LMNA P02545 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAOA P21397 3/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7759490 0.83 PNMT (0.44) PGRPNMTNPC1RAB9AALDH1A1
SCHEMBL30341585 0.81 PNMT (0.49) PGRPNMTNPC1RAB9AALDH1A1
SCHEMBL1509311 0.81 PNMT (0.49) PGRPNMTNPC1RAB9AALDH1A1
Hydrochloric Acid SCHEMBL7195499 0.81 PGR (0.40) PGRPNMTNPC1RAB9AALDH1A1
Hydrochloric Acid SCHEMBL2870709 0.80 PNMT (0.47) PGRPNMTNPC1RAB9AALDH1A1
SCHEMBL7195505 0.79 PGR (0.38) PGRPNMTNPC1RAB9AALDH1A1
SCHEMBL28162359 0.78 PNMT (0.40) PGRPNMTNPC1RAB9AALDH1A1
SCHEMBL22263591 0.76 PNMT (0.57) PGRPNMTNPC1RAB9AALDH1A1
SCHEMBL9811549 0.72 PNMT (0.40) PGRPNMTNPC1RAB9AALDH1A1
SCHEMBL30103334 0.71 PNMT (0.63) PGRPNMTNPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110505962-A The production method of original edition of lithographic printing plate and lithographic printing plate FUJIFILM CORP 2019-11-26 CN disclosed
CN-107206822-B Recording materials and recording sheet 日本曹达株式会社 2019-11-26 CN disclosed
CN-110402201-A Linerless thermosensitive recording body package body RICOH CO LTD 2019-11-01 CN disclosed
CN-110271310-A Thermal recording material and its manufacturing method 卡西欧计算机株式会社 2019-09-24 CN disclosed
CN-107267046-B A kind of thermo-chromatic and preparation method thereof, application 广东韩亚薄膜科技有限公司 2019-07-02 CN disclosed
CN-109863034-A Original edition of lithographic printing plate, the production method of lithographic printing plate and lithographic process 富士胶片株式会社 2019-06-07 CN disclosed
CN-109476946-A Optics fadout color-changing composition and its method made and used 西甘产业股份有限公司 2019-03-15 CN disclosed
CN-109328143-A THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE 株式会社理光 2019-02-12 CN disclosed
CN-105026171-B Thermal recording medium 株式会社理光 2018-12-14 CN disclosed
CN-108699344-A Color composition, original edition of lithographic printing plate, the manufacturing method of lithographic printing plate and colour rendering compound 富士胶片株式会社 2018-10-23 CN disclosed
CN-108349282-A Thermal recording medium and diphenyl sulphone (DPS) 日本化药株式会社 2018-07-31 CN disclosed
CN-105189132-B Thermosensitive recording medium exhibiting gold metallic tone and/or thermosensitive recording medium exhibiting two different tones 王子控股株式会社 2018-06-26 CN disclosed
WO-2004037654-A2 THERMOPLASTIC CONTAINERS EXHIBITING EXCELLENT PROTECTION TO VARIOUS ULTRAVIOLET SUSCEPTIBLE COMPOUNDS MILLIKEN & COMPANY (US) 2004-05-06 WO disclosed