SCHEMBL7759583

SCHEMBL7759583

C=Cc1ccc(-c2[c]ccc(C)c2-c2ccc(C=C)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
HDAC8 Q9BY41 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7070227 0.76 BRD4 (0.36) ALDH1A1
SCHEMBL10415094 0.69 MAPT (0.40) ALDH1A1TSHR
SCHEMBL1903580 0.67 ALDH1A1 (0.43) ALDH1A1HDAC8TSHR
SCHEMBL5321136 0.66 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL583978 0.65 ALDH1A1 (0.79) ALDH1A1HDAC8TSHR
SCHEMBL593791 0.65 ALDH1A1 (0.79) ALDH1A1HDAC8TSHR
SCHEMBL157101 0.64 ALDH1A1 (0.58) ALDH1A1HDAC8TSHR
SCHEMBL2834322 0.63 PTGS2 (0.35)
Water SCHEMBL7178879 0.62 ALDH1A1 (0.73) ALDH1A1HDAC8TSHR
SCHEMBL14877347 0.62 ALDH1A1 (0.62) ALDH1A1HDAC8TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1085022-A1 A method of manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via Si-C- bonds Dow Corning Asia, Ltd. (JP) 2001-03-21 EP disclosed
US-6060620-A Method for manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via SI--C bonds DOW CORNING ASIA, LTD. (JP) 2000-05-09 US disclosed