Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | KLK1 | P06870 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19062411 | 0.84 | CTRB1 (0.62) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL11677527 | 0.83 | CTSL (0.64) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL30460502 | 0.82 | ATM (0.68) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL21469067 | 0.82 | ATM (0.68) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL7719287 | 0.82 | ATM (0.77) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL7291093 | 0.82 | CTRB1 (0.56) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL1362502 | 0.82 | ATM (0.77) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL3255533 | 0.82 | ATM (0.77) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL8530402 | 0.82 | ATM (0.68) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL434233 | 0.82 | ATM (0.77) | CTRB1ALDH1A1CYP1A2CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639586-B1 | Phosphonic acid derivatives, process for their preparation and pharmaceutical compositions comprising them | ADIR (FR) | 2001-03-21 | — | — | EP | claimed |
| EP-0639586-A1 | Phosphonic acid derivatives, process for their preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 1995-02-22 | — | — | EP | claimed |