Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759928 | 0.86 | KCNH2 (0.32) | LMNA | |
| SCHEMBL7758069 | 0.81 | — | — | |
| SCHEMBL7759947 | 0.81 | RAB9A (0.34) | KDM4E | |
| SCHEMBL8073971 | 0.79 | KDM4E (0.36) | KDM4EGAALMNAMAPK1L3MBTL1 | |
| SCHEMBL8454689 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL8452872 | 0.75 | ALDH1A1 (0.34) | KDM4ELMNAMAPK1 | |
| SCHEMBL8916577 | 0.75 | KDM4E (0.33) | KDM4EGAALMNAMAPK1L3MBTL1 | |
| SCHEMBL7758954 | 0.73 | ALDH1A1 (0.31) | KDM4ELMNAMAPK1 | |
| SCHEMBL7755500 | 0.73 | ESR2 (0.36) | — | |
| SCHEMBL7751125 | 0.73 | MRGPRX4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711777-B1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHINETSU CHEMICAL CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0711777-A1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |