Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 9/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TK2 | O00142 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759934 | 1.00 | TK1 (0.43) | TK1HPGDTK2LMNAPKM | |
| SCHEMBL7756577 | 0.85 | ALDH1A1 (0.44) | TK1HPGDLMNAPKMALDH1A1 | |
| SCHEMBL7756583 | 0.85 | ALDH1A1 (0.44) | TK1HPGDLMNAPKMALDH1A1 | |
| SCHEMBL599846 | 0.84 | ALDH1A1 (0.41) | HPGDLMNAPKMALDH1A1TSHR | |
| SCHEMBL7756656 | 0.83 | LMNA (0.38) | TK1HPGDLMNAPKMALDH1A1 | |
| SCHEMBL7756652 | 0.83 | LMNA (0.38) | TK1HPGDLMNAPKMALDH1A1 | |
| SCHEMBL7757667 | 0.82 | LMNA (0.52) | HPGDLMNAPKMALDH1A1TSHR | |
| SCHEMBL7758853 | 0.80 | LMNA (0.38) | TK1HPGDLMNAPKMALDH1A1 | |
| SCHEMBL9597854 | 0.77 | ALDH1A1 (0.53) | TK1HPGDLMNAPKMALDH1A1 | |
| SCHEMBL8760090 | 0.76 | UPP1 (0.49) | ALDH1A1TSHRMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |
| US-5747500-A | VIRICIDES FOR AIDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-05-05 | — | — | US | disclosed |
| WO-1995018109-A1 | NOVEL ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-06 | — | — | WO | disclosed |