Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 6/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454873 | 0.97 | EPHX2 (0.48) | EPHX2IDO1SYKHDAC8KMT2A | |
| SCHEMBL7756814 | 0.89 | FFAR1 (0.53) | EPHX2IDO1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL14717782 | 0.89 | EPHX2 (0.56) | EPHX2IDO1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL14685742 | 0.87 | SIRT2 (0.51) | EPHX2IDO1KMT2ASIRT2FFAR1 | |
| SCHEMBL6289443 | 0.84 | SMN1; SMN2 (0.49) | EPHX2IDO1HDAC8KMT2ACYP4F2 | |
| SCHEMBL2776004 | 0.83 | TDP1 (0.51) | EPHX2IDO1SIRT2FFAR1POLB | |
| SCHEMBL12370805 | 0.81 | SYK (0.50) | SYKCYP4F2CYP4A11FFAR1 | |
| SCHEMBL7760724 | 0.81 | F2RL1 (0.63) | KMT2AFFAR1POLB | |
| SCHEMBL9861207 | 0.80 | KMT2A (0.49) | HDAC8KMT2ACYP4F2CYP4A11SIRT2 | |
| SCHEMBL2569441 | 0.80 | L3MBTL1 (0.55) | EPHX2IDO1KMT2ACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755916-B1 | Process for the preparation of amine compound | FUJI XEROX CO LTD (JP) | 2001-04-25 | — | — | EP | disclosed |
| EP-0755916-A2 | Process for the preparation of amine compound | FUJI XEROX CO., LTD. (JP) | 1997-01-29 | — | — | EP | disclosed |