Sugi Predict

Sugi Predict / Compounds / SCHEMBL6289443

SCHEMBL6289443

SCHEMBL6289443

COC(=O)CCc1ccc(Nc2ccc(C)c(C)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ NPC1 O15118 2/20 0.49
▸ RAB9A P51151 2/20 0.49
▸ MAPT P10636 3/20 0.48
▸ EPHX2 P34913 1/20 0.47
▸ IDO1 P14902 1/20 0.45
▸ POLB P06746 2/20 0.45
▸ KMT2A Q03164 3/20 0.45
▸ MEN1 O00255 2/20 0.45
▸ HTT P42858 1/20 0.45
▸ SIRT2 Q8IXJ6 1/20 0.44
▸ ALDH1A1 P00352 3/20 0.43
▸ GAA P10253 2/20 0.43
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ LMNA P02545 1/20 0.42
▸ CYP4F2 P78329 1/20 0.42
▸ CYP4A11 Q02928 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ HDAC3 O15379 1/20 0.41
▸ HDAC4 P56524 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7761596 0.92 EPHX2 (0.49) SMN1; SMN2NPC1RAB9AMAPTEPHX2
SCHEMBL14717782 0.87 EPHX2 (0.56) MAPTEPHX2IDO1KMT2AHTT
SCHEMBL4883797 0.85 FFAR1 (0.54) POLBALDH1A1
SCHEMBL7763192 0.85 SMN1; SMN2 (0.66) SMN1; SMN2NPC1RAB9AMAPTEPHX2
SCHEMBL7756814 0.84 FFAR1 (0.53) MAPTEPHX2IDO1KMT2AMEN1
SCHEMBL8969138 0.84 NPC1 (0.49) SMN1; SMN2NPC1RAB9AMAPTPOLB
SCHEMBL7759977 0.84 EPHX2 (0.48) EPHX2IDO1POLBKMT2ASIRT2
SCHEMBL5454873 0.84 EPHX2 (0.48) EPHX2IDO1KMT2ASIRT2CYP4F2
SCHEMBL14685742 0.83 SIRT2 (0.51) SMN1; SMN2NPC1RAB9AMAPTEPHX2
SCHEMBL12370801 0.82 HRH3 (0.49) SMN1; SMN2NPC1RAB9AMAPTIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9188885-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-11-17 — — US disclosed
US-9188885-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-11-17 — — US disclosed
US-9188885-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-11-17 — — US disclosed
US-20140079435-A1 NOVEL REACTIVE COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PRODUCING THE SAME, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-03-20 — — US disclosed
US-20140079435-A1 NOVEL REACTIVE COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PRODUCING THE SAME, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-03-20 — — US disclosed
US-20140079435-A1 NOVEL REACTIVE COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PRODUCING THE SAME, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-03-20 — — US disclosed
US-8669029-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-11 — — US disclosed
US-8669029-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-11 — — US disclosed
US-8669029-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-11 — — US disclosed
US-20130052573-A1 NOVEL REACTIVE COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PRODUCING THE SAME, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 — — US disclosed
US-20030091924-A1 Image forming method FUJI XEROX CO., LTD. (JP) 2003-05-15 — — US disclosed
EP-0755916-B1 Process for the preparation of amine compound FUJI XEROX CO LTD (JP) 2001-04-25 — — EP disclosed
EP-0713149-B1 Electrophotographic photoreceptor using charge transporting copolyester FUJI XEROX CO LTD (JP) 2000-08-23 — — EP disclosed
EP-0686879-B1 Charge-transporting polymer and organic electronic device using the same FUJI XEROX CO LTD (JP) 2000-05-24 — — EP disclosed
US-5736285-A PHOTOSENSITIVE LAYER CONTAINS CHARGE TRANSPORTING POLYESTER AND ATLEAST ONE BISAZO PIGMENT; WEAR RESISTANCE AND ELECTRIC STABILITY FUJI XEROX CO., LTD. (JP) 1998-04-07 — — US disclosed
US-5731118-A Charge transporting random copolyester resin, process for producing the same and organic electronic device using the same FUJI XEROX CO., LTD. (JP) 1998-03-24 — — US disclosed
US-5604064-A USEFUL IN ELECTROPHOTOGRAPHIC PHOTORECEPTORS FUJI XEROX CO., LTD. (JP) 1997-02-18 — — US disclosed
EP-0755916-A2 Process for the preparation of amine compound FUJI XEROX CO., LTD. (JP) 1997-01-29 — — EP disclosed
EP-0713149-A1 Organic electronic device using charge transporting copolyester FUJI XEROX CO., LTD. (JP) 1996-05-22 — — EP disclosed
EP-0686879-A1 Charge-transporting polymer and organic electronic device using the same FUJI XEROX CO., LTD. (JP) 1995-12-13 — — EP disclosed