SCHEMBL7760724

SCHEMBL7760724

COC(=O)CCc1ccc(Nc2ccc(OC)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 1/20 0.63
FFAR1 O14842 2/20 0.58
ALDH1A1 P00352 3/20 0.58
HTT P42858 1/20 0.58
POLB P06746 1/20 0.55
MAPT P10636 4/20 0.55
GAA P10253 3/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
MAPK1 P28482 2/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
KDM4E B2RXH2 1/20 0.55
THRB P10828 1/20 0.55
RECQL P46063 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.52
LMNA P02545 2/20 0.52
MEN1 O00255 1/20 0.52
HPGD P15428 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14717782 0.92 EPHX2 (0.56) F2RL1FFAR1ALDH1A1HTTMAPT
SCHEMBL1445627 0.92 F2RL1 (0.73) F2RL1FFAR1ALDH1A1HTTPOLB
SCHEMBL2277479 0.87 F2RL1 (0.67) F2RL1FFAR1ALDH1A1HTTPOLB
SCHEMBL7756814 0.85 FFAR1 (0.53) F2RL1FFAR1ALDH1A1MAPTL3MBTL1
SCHEMBL2776004 0.85 TDP1 (0.51) FFAR1ALDH1A1HTTPOLBMAPT
SCHEMBL3468096 0.84 F2RL1 (0.63) F2RL1ALDH1A1POLBMAPTL3MBTL1
SCHEMBL31324194 0.83 ALDH1A1 (0.63) ALDH1A1HTTPOLBMAPTGAA
SCHEMBL22922181 0.82 CYP4F2 (0.59) F2RL1ALDH1A1HTTPOLBMAPT
SCHEMBL1274985 0.81 ALOX5 (0.66) F2RL1ALDH1A1POLBHPGD
SCHEMBL6308951 0.81 FFAR1 (0.56) FFAR1ALDH1A1MAPTGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0755916-B1 Process for the preparation of amine compound FUJI XEROX CO LTD (JP) 2001-04-25 EP disclosed
EP-0686879-B1 Charge-transporting polymer and organic electronic device using the same FUJI XEROX CO LTD (JP) 2000-05-24 EP disclosed
US-5731118-A Charge transporting random copolyester resin, process for producing the same and organic electronic device using the same FUJI XEROX CO., LTD. (JP) 1998-03-24 US disclosed
US-5604064-A USEFUL IN ELECTROPHOTOGRAPHIC PHOTORECEPTORS FUJI XEROX CO., LTD. (JP) 1997-02-18 US disclosed
EP-0755916-A2 Process for the preparation of amine compound FUJI XEROX CO., LTD. (JP) 1997-01-29 EP disclosed
EP-0686879-A1 Charge-transporting polymer and organic electronic device using the same FUJI XEROX CO., LTD. (JP) 1995-12-13 EP disclosed