Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | HTT | P42858 | 3/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289816 | 0.88 | KMT2A (0.59) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL7756917 | 0.87 | KMT2A (0.72) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL7760912 | 0.85 | MEN1 (0.74) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL23269308 | 0.85 | HTT (0.74) | KMT2AMEN1HTTLMNAHSD17B10 | |
| SCHEMBL7756911 | 0.84 | LMNA (0.54) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL3455654 | 0.84 | HTT (1.00) | KMT2AMEN1HTTLMNASMN1; SMN2 | |
| SCHEMBL6293769 | 0.79 | KMT2A (0.61) | KMT2AMEN1HTTLMNAHSD17B10 | |
| SCHEMBL10722273 | 0.77 | L3MBTL1 (0.74) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL15966080 | 0.75 | L3MBTL1 (0.62) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL11724672 | 0.75 | KMT2A (0.65) | KMT2AMEN1HTTL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |