Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6293769 | 0.90 | KMT2A (0.61) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL7756917 | 0.88 | KMT2A (0.72) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL10789644 | 0.88 | LMNA (0.62) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL7760010 | 0.85 | KMT2A (0.76) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL7130439 | 0.84 | LMNA (0.72) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL23269308 | 0.84 | HTT (0.74) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL3455654 | 0.83 | HTT (1.00) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL20964612 | 0.82 | KMT2A (0.57) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL20964592 | 0.80 | KDM4E (0.50) | MEN1KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL6291059 | 0.80 | ALDH1A1 (0.55) | MEN1KMT2AHTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |