Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.77 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.60 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.60 |
| ▸ | RARB | P10826 | 9/20 | 0.56 |
| ▸ | RARG | P13631 | 8/20 | 0.56 |
| ▸ | RARA | P10276 | 7/20 | 0.56 |
| ▸ | RXRB | P28702 | 6/20 | 0.55 |
| ▸ | RXRG | P48443 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30012842 | 0.87 | RXRA (1.00) | RXRACYP26A1CYP26B1RARBRARG | |
| SCHEMBL3453249 | 0.87 | RXRA (1.00) | RXRACYP26A1CYP26B1RARBRARG | |
| SCHEMBL7889505 | 0.85 | RXRA (0.60) | RXRACYP26A1CYP26B1RARBRARG | |
| SCHEMBL7760432 | 0.82 | RXRA (0.69) | RXRACYP26A1CYP26B1RARBRARG | |
| SCHEMBL29827631 | 0.78 | RARB (0.81) | RXRACYP26A1CYP26B1RARBRARG | |
| SCHEMBL846110 | 0.78 | RARB (0.81) | RXRACYP26A1CYP26B1RARBRARG | |
| SCHEMBL20398875 | 0.78 | RXRA (0.69) | RXRACYP26A1CYP26B1RARBRARG | |
| SCHEMBL7761329 | 0.78 | RARB (0.80) | RXRACYP26A1CYP26B1RARBRARG | |
| SCHEMBL7759879 | 0.78 | CYP26B1 (0.64) | RXRACYP26A1CYP26B1RARBRARG | |
| SCHEMBL7759877 | 0.78 | CYP26B1 (0.64) | RXRACYP26A1CYP26B1RARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915823-B1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CT INTERNAT DE (FR) | 2001-04-18 | — | — | EP | disclosed |
| EP-0915823-A1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998022423-A1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-05-28 | — | — | WO | disclosed |