Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3028940 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10MAPTHPGD | |
| SCHEMBL28243372 | 0.80 | TDP1 (0.52) | CTSBTDP1ALDH1A1ARTSHR | |
| SCHEMBL1562772 | 0.78 | TDP1 (0.57) | CTSBTDP1ALDH1A1ARTSHR | |
| SCHEMBL7788656 | 0.76 | TDP1 (0.80) | CTSBTDP1ALDH1A1ARTSHR | |
| SCHEMBL3092837 | 0.76 | TDP1 (0.55) | CTSBTDP1ALDH1A1ARTSHR | |
| SCHEMBL3092848 | 0.76 | TDP1 (0.55) | CTSBTDP1ALDH1A1ARTSHR | |
| SCHEMBL5577224 | 0.76 | TDP1 (0.55) | CTSBTDP1ALDH1A1ARTSHR | |
| SCHEMBL7289593 | 0.76 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10MAPTHPGD | |
| SCHEMBL27500598 | 0.75 | CTSB (0.50) | CTSBTDP1ALDH1A1ARTSHR | |
| SCHEMBL7324252 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRHSD17B10MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001091796-A2 | METHODS, COMPOUNDS AND COMPOSITIONS FOR TREATING GOUT | GUILFORD PHARMACEUTICALS INC. (US) | 2001-12-06 | — | — | WO | disclosed |