Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289593 | 0.94 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDSIGMAR1L3MBTL1 | |
| SCHEMBL7324252 | 0.93 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDSIGMAR1L3MBTL1 | |
| SCHEMBL4154406 | 0.93 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDSIGMAR1L3MBTL1 | |
| SCHEMBL1802353 | 0.88 | ALDH1A1 (0.62) | ALDH1A1TSHRHPGDSIGMAR1L3MBTL1 | |
| SCHEMBL3202573 | 0.83 | ALDH1A1 (0.72) | ALDH1A1TSHRHPGDSIGMAR1L3MBTL1 | |
| SCHEMBL8867793 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRHPGDSIGMAR1L3MBTL1 | |
| SCHEMBL34723 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TSHRHPGDL3MBTL1HTT | |
| SCHEMBL7760229 | 0.81 | CTSB (0.49) | ALDH1A1TSHRHPGDMAPTHSD17B10 | |
| SCHEMBL6259352 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TSHRHPGDSIGMAR1L3MBTL1 | |
| SCHEMBL4690575 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TSHRHPGDSIGMAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786448-A | FOR SCREENING, SYNTHESIZING PEPTIDE DERIVATIVES | TREGA BIOSCIENCES, INC. (US) | 1998-07-28 | — | — | US | claimed |
| WO-1998019693-A1 | COMBINATORIAL LIBRARIES OF CYCLIC UREA AND CYCLIC THIOUREA DERIVATIVES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-05-14 | — | — | WO | claimed |
| EP-2825586-A2 | PROCESS FOR THE ENZYMATIC DEGRADATION OF POLYURETHANES | Eurofoam GmbH (AT) | 2015-01-21 | — | — | EP | disclosed |
| CN-101522657-B | STAT3/5 activation inhibitor | OTSUKA PHARMACEUTICAL CO.,LTD. (JP) | 2014-10-15 | — | — | CN | disclosed |
| EP-1957073-B1 | MEDICINAL DRUG | OTSUKA PHARMA CO LTD (JP) | 2014-04-23 | — | — | EP | disclosed |
| US-8551999-B2 | Heterocyclic compound and pharmaceutical composition thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-10-08 | — | — | US | disclosed |
| WO-2013134801-A2 | PROCESS FOR THE MATERIAL UTILIZATION OF POLYURETHANES | EUROFOAM GMBH (AT) | 2013-09-19 | — | — | WO | disclosed |
| EP-2612858-A1 | STAT3/5 activation inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-07-10 | — | — | EP | disclosed |
| CN-1993339-B | Aromatic compound | OTSUKA PHARMA CO LTD | 2013-05-22 | — | — | CN | disclosed |
| US-20120322807-A1 | STAT3/5 ACTIVATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. | 2012-12-20 | — | — | US | disclosed |
| US-20120238750-A1 | AROMATIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. | 2012-09-20 | — | — | US | disclosed |
| CN-1353694-A | Alpha-substituted carboxylic acid derivatives | SANKYO CO (JP) | 2002-06-12 | — | — | CN | disclosed |
| EP-1181279-A1 | DIKETODIAZACYCLIC COMPOUNDS, DIAZACYCLIC COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2002-02-27 | — | — | EP | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000069830-A1 | DIKETODIAZACYCLIC COMPOUNDS, DIAZACYCLIC COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2000-11-23 | — | — | WO | disclosed |
| US-5786448-A | FOR SCREENING, SYNTHESIZING PEPTIDE DERIVATIVES | TREGA BIOSCIENCES, INC. (US) | 1998-07-28 | — | — | US | disclosed |
| WO-1998019693-A1 | COMBINATORIAL LIBRARIES OF CYCLIC UREA AND CYCLIC THIOUREA DERIVATIVES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-05-14 | — | — | WO | disclosed |
| EP-0623599-A1 | Optical sensors for the determination of cations | CIBA-GEIGY AG (CH) | 1994-11-09 | — | — | EP | disclosed |
| US-4670218-A | HOMOGENEOUS HYDROPHOBIC SUBSTANCE, IONOPHORE CAPABLE OF COMPL EXING WITH THE ION REPORTER SUBSTANCE | MILES LABORATORIES, INC. (US) | 1987-06-02 | — | — | US | disclosed |
| US-4645744-A | FORMING COMPLEX WITH IONOPHORE ON CARRIER MATRIX | MILES LABORATORIES, INC. (US) | 1987-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238750-A1 | AROMATIC COMPOUND | CBR1, CBR3, CYP1A1 | ALDH1A1 565/4885TSHR 1585/4885HPGD 2527/4885 |
| US-20120322807-A1 | STAT3/5 ACTIVATION INHIBITOR | STAT3, JAK2, STAT1 | ALDH1A1 2295/4885TSHR 643/4885HPGD 3828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.