SCHEMBL7760376

SCHEMBL7760376

CCCC(CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC

nearest known ligand 0.83

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 17/20 0.83
MMP1 P03956 17/20 0.83
MMP2 P08253 12/20 0.83
MMP7 P09237 9/20 0.83
FCER2 P06734 2/20 0.82
MMP8 P22894 9/20 0.81
MMP9 P14780 4/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4813526 1.00 MMP3 (0.83) MMP3MMP1MMP2MMP7FCER2
SCHEMBL8400000 0.91 MMP2 (1.00) MMP3MMP1MMP2MMP7MMP8
SCHEMBL8399999 0.91 MMP2 (1.00) MMP3MMP1MMP2MMP7MMP8
SCHEMBL8396700 0.91 MMP2 (1.00) MMP3MMP1MMP2MMP7MMP8
SCHEMBL8396703 0.91 MMP2 (1.00) MMP3MMP1MMP2MMP7MMP8
SCHEMBL8397172 0.91 MMP2 (1.00) MMP3MMP1MMP2MMP7MMP8
SCHEMBL8828138 0.90 MMP3 (1.00) MMP3MMP1MMP2MMP7FCER2
SCHEMBL9288857 0.88 MMP3 (1.00) MMP3MMP1MMP2MMP7FCER2
SCHEMBL2638942 0.87 MMP1 (1.00) MMP3MMP1MMP2MMP7FCER2
SCHEMBL2638846 0.86 MMP3 (0.80) MMP3MMP1MMP2MMP7FCER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1079819-A1 HYDROXAMIC ACID DERIVATIVES AS ANTIBACTERIALS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2001-03-07 EP disclosed
WO-1999059568-A1 HYDROXAMIC ACID DERIVATIVES AS ANTIBACTERIALS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1999-11-25 WO disclosed