Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10387228 | 1.00 | GPR84 (0.48) | GPR84FFAR1FFAR4GAACES2 | |
| SCHEMBL7764641 | 1.00 | GPR84 (0.48) | GPR84FFAR1FFAR4GAACES2 | |
| SCHEMBL11745437 | 0.98 | GPR84 (0.44) | GPR84FFAR1FFAR4GAACES2 | |
| SCHEMBL22468682 | 0.96 | GAA (0.48) | GPR84FFAR1FFAR4GAACES2 | |
| SCHEMBL1566659 | 0.90 | — | — | |
| SCHEMBL7713583 | 0.90 | CES2 (0.50) | GAACES2CYP2C19EPHX2CYP4F2 | |
| SCHEMBL18660231 | 0.90 | CES2 (0.50) | GAACES2CYP2C19EPHX2CYP4F2 | |
| SCHEMBL19875980 | 0.88 | MEN1 (0.50) | GPR84FFAR1FFAR4GAACES2 | |
| SCHEMBL22922164 | 0.87 | CES2 (0.48) | GAACES2CYP2C19EPHX2CYP4F2 | |
| SCHEMBL10001230 | 0.87 | CES2 (0.46) | CES2CYP2C19EPHX2CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1099698-A1 | Macrocyclic oxalactones ( dioxacycloalkan-ones ) and their use as perfumes | PFW AROMA CHEMICALS B.V. (NL) | 2001-05-16 | — | — | EP | disclosed |