⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL638552 | 0.80 | OPRM1 (0.39) | — | |
| SCHEMBL31548667 | 0.77 | — | — | |
| SCHEMBL444986 | 0.77 | — | — | |
| SCHEMBL31142031 | 0.76 | — | — | |
| SCHEMBL17024077 | 0.75 | — | — | |
| SCHEMBL2576165 | 0.75 | — | — | |
| SCHEMBL4436682 | 0.75 | — | — | |
| SCHEMBL9840360 | 0.75 | CHRNB2 (0.38) | — | |
| SCHEMBL15261078 | 0.74 | OPRM1 (0.35) | — | |
| SCHEMBL35088 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150265977-A1 | FOULING RESISTANT MEMBRANES FOR WATER TREATMENT | GENERAL ELECTRIC COMPANY (US) | 2015-09-24 | — | — | US | disclosed |
| EP-0709392-B1 | Process for the preparation of 3-halogeno- or -pseudohalogeno-alkylsilane esters, respectively | DEGUSSA (DE) | 2001-05-16 | — | — | EP | disclosed |
| US-5616762-A | Process for the preparation of 3-halo-and pseudohalo-alkylsilane esters | HUELS AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |
| EP-0709392-A1 | Process for the preparation of 3-halogeno- or -pseudohalogeno-alkylsilane esters, respectively | HÜLS AKTIENGESELLSCHAFT (DE) | 1996-05-01 | — | — | EP | disclosed |