Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 13/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 13/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 9/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326204 | 0.81 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL15407473 | 0.81 | — | — | |
| SCHEMBL3392409 | 0.77 | — | — | |
| SCHEMBL9326195 | 0.77 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL444986 | 0.77 | — | — | |
| SCHEMBL31548667 | 0.77 | — | — | |
| SCHEMBL7760414 | 0.75 | — | — | |
| SCHEMBL638552 | 0.75 | OPRM1 (0.39) | — | |
| SCHEMBL57520 | 0.73 | — | — | |
| SCHEMBL20658015 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017636-A | Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-21 | — | — | US | claimed |
| US-5017636-A | Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |