⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5005558 | 0.79 | RAB9A (0.33) | — | |
| SCHEMBL4999740 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL23701148 | 0.73 | — | — | |
| SCHEMBL1640058 | 0.72 | KDM1A (0.32) | — | |
| SCHEMBL9856473 | 0.72 | — | — | |
| SCHEMBL28426339 | 0.70 | — | — | |
| SCHEMBL6294995 | 0.70 | KDM1A (0.31) | — | |
| SCHEMBL23532623 | 0.70 | KDM1A (0.31) | — | |
| SCHEMBL6291550 | 0.70 | KDM1A (0.31) | — | |
| SCHEMBL23532425 | 0.70 | KDM1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017170-B1 | IMPROVED PROCESS FOR THE PREPARATION OF CEPHAMYCIN ANTIBIOTICS | MERCK & CO. INC. (US) | 1983-04-13 | — | — | EP | claimed |
| EP-0017170-A1 | Improved process for the preparation of cephamycin antibiotics | MERCK & CO. INC. (US) | 1980-10-15 | — | — | EP | claimed |
| US-4220762-A | Process for the preparation of cephamycin antibiotics | MERCK & CO., INC. (US) | 1980-09-02 | — | — | US | claimed |
| EP-0882007-B1 | PREPARATION OF ALPHA-FLUOROKETONES | F2 CHEMICALS LTD (GB) | 2001-03-14 | — | — | EP | disclosed |
| US-6031139-A | Preparation of α-fluoroketones | F2 CHEMICALS LIMITED (GB) | 2000-02-29 | — | — | US | disclosed |
| EP-0882007-A1 | PREPARATION OF ALPHA-FLUOROKETONES | F2 Chemicals Limited (GB) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997046508-A1 | PREPARATION OF ALPHA-FLUOROKETONES | F2 CHEMICALS LIMITED (GB) | 1997-12-11 | — | — | WO | disclosed |
| EP-0017170-B1 | IMPROVED PROCESS FOR THE PREPARATION OF CEPHAMYCIN ANTIBIOTICS | MERCK & CO. INC. (US) | 1983-04-13 | — | — | EP | disclosed |
| EP-0017170-A1 | Improved process for the preparation of cephamycin antibiotics | MERCK & CO. INC. (US) | 1980-10-15 | — | — | EP | disclosed |
| US-4220762-A | Process for the preparation of cephamycin antibiotics | MERCK & CO., INC. (US) | 1980-09-02 | — | — | US | disclosed |