SCHEMBL7760443

SCHEMBL7760443

O=C(O)c1ccc(C(=O)O)c(-c2cccc(-c3c(C(=O)O)ccc(C(=O)O)c3C(=O)O)c2)c1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 3/20 0.46
HNF4A P41235 3/20 0.44
KMO O15229 1/20 0.42
WDR5 P61964 1/20 0.41
ALDH1A1 P00352 4/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.41
CDC25B P30305 2/20 0.40
MCL1 Q07820 2/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
DHFR P00374 1/20 0.40
CDC25A P30304 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30395913 0.88 WDR5 (0.48) ACMSDHNF4AWDR5ALDH1A1HPGD
SCHEMBL6755748 0.88 WDR5 (0.48) ACMSDHNF4AWDR5ALDH1A1HPGD
SCHEMBL18042647 0.87 ACMSD (0.52) ACMSDHNF4AKMOWDR5ALDH1A1
SCHEMBL2791938 0.83 CYP1A2 (0.46) ACMSDHNF4AWDR5ALDH1A1HPGD
SCHEMBL8949874 0.78 DHODH (0.46) ACMSDHNF4AKMOALDH1A1MEN1
SCHEMBL10783650 0.78 FOLH1 (0.54) KMO
SCHEMBL10783606 0.78 FOLH1 (0.54) KMO
SCHEMBL9813471 0.78 ACMSD (0.53) ACMSDHNF4AKMOCDC25BMCL1
SCHEMBL17744866 0.77 MCL1 (0.51) HNF4AALDH1A1MEN1GAAHPGD
SCHEMBL17744798 0.77 MCL1 (0.51) HNF4AALDH1A1MEN1GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1103366-A1 OPEN TYPE POLYIMIDE MOLDED PRODUCT AND PRODUCTION METHOD THEREOF DU PONT-TORAY COMPANY, LTD. (JP) 2001-05-30 EP disclosed