Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.46 |
| ▸ | IKBKB | O14920 | 3/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374101 | 0.92 | IKBKB (0.47) | DHODHIKBKBBCAT2ALDH1A1GAA | |
| SCHEMBL169868 | 0.92 | IKBKB (0.47) | DHODHIKBKBBCAT2ALDH1A1GAA | |
| SCHEMBL18042647 | 0.90 | ACMSD (0.52) | ACMSDMEN1ALDH1A1GAAHPGD | |
| SCHEMBL4151580 | 0.81 | BCAT2 (0.59) | IKBKBBCAT2MEN1ALDH1A1HPGD | |
| SCHEMBL27919911 | 0.81 | MAP4K4 (0.50) | IKBKBBCAT2MEN1ALDH1A1MCL1 | |
| SCHEMBL7063111 | 0.81 | PARP1 (0.52) | IKBKBBCAT2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL17744780 | 0.81 | MCL1 (0.62) | ACMSDMEN1ALDH1A1GAAHPGD | |
| SCHEMBL10701680 | 0.79 | CHEK1 (0.47) | IKBKBALDH1A1GAAHPGDSIRT2 | |
| SCHEMBL10782131 | 0.78 | KMO (0.62) | GAAHPGDKMOCYP1A2CYP2C9 | |
| SCHEMBL7760443 | 0.78 | ACMSD (0.46) | DHODHACMSDMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489611-A | ADMINISTERING A RETINOID COMPOUND | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |