Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29690426 | 0.76 | NOTUM (0.48) | TSHRALDH1A1HPGDMAPTGAA | |
| SCHEMBL3402653 | 0.76 | NOTUM (0.48) | TSHRALDH1A1HPGDMAPTGAA | |
| SCHEMBL8168627 | 0.76 | MAOA (0.46) | TSHRCYP3A4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2024086 | 0.76 | TSHR (0.46) | TSHRCYP3A4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10216765 | 0.73 | CYP3A4 (0.43) | TSHRCYP3A4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8025852 | 0.71 | CYP3A4 (0.41) | TSHRCYP3A4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8391771 | 0.71 | CYP3A4 (0.41) | TSHRCYP3A4ALDH1A1HPGDCYP1A2 | |
| Acenaphthene SCHEMBL9017 | 0.71 | TSHR (0.57) | TSHRCYP3A4ALDH1A1HPGDHSD17B10 | |
| Acenaphthene SCHEMBL598252 | 0.71 | TSHR (0.57) | TSHRCYP3A4ALDH1A1HPGDHSD17B10 | |
| Acenaphthene SCHEMBL3416108 | 0.71 | TSHR (0.57) | TSHRCYP3A4ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086973-A2 | Polyimide gas separation membranes | PRAXAIR TECHNOLOGY, INC. (US) | 2001-03-28 | — | — | EP | disclosed |