Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026888 | 0.81 | CYP1A2 (0.36) | MAPTCYP1A2CYP1A1CYP1B1 | |
| SCHEMBL1101990 | 0.80 | MEN1 (0.55) | TSHRMEN1KMT2AHRH3KCNH2 | |
| SCHEMBL22221914 | 0.80 | MEN1 (0.36) | MEN1KMT2AHRH3KCNH2ALDH1A1 | |
| SCHEMBL8036747 | 0.79 | KCNH2 (0.37) | KCNH2TMEM97SIGMAR1 | |
| SCHEMBL23716163 | 0.77 | HRH3 (0.43) | CYP3A4TSHRMEN1KMT2AHRH3 | |
| SCHEMBL8168627 | 0.76 | MAOA (0.46) | CYP3A4TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL8027138 | 0.75 | KDM4E (0.33) | MEN1KMT2AKCNH2ALDH1A1HPGD | |
| SCHEMBL8037860 | 0.74 | HTR1A (0.38) | CYP3A4TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL1615567 | 0.74 | KMT2A (0.46) | CYP3A4MEN1KMT2AHRH3KCNH2 | |
| SCHEMBL26192019 | 0.74 | MEN1 (0.50) | TSHRMEN1KMT2AHRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230270750-A1 | CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-08-31 | — | — | US | disclosed |
| US-7482468-B2 | Imidazole and benzimidazole derivatives useful as histamine H3 antagonists | SCHERING CORPORATION (US) | 2009-01-27 | — | — | US | disclosed |
| US-7482468-B2 | Imidazole and benzimidazole derivatives useful as histamine H3 antagonists | SCHERING CORPORATION (US) | 2009-01-27 | — | — | US | disclosed |
| US-20080317712-A1 | ARYLPIPERIDINYL AND ARYLPYRROLIDINYL TRIPEPTIDE HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2008-12-25 | — | — | US | disclosed |
| US-20080279821-A1 | ARYLPIPERIDINYL AND ARYLPYRROLIDINYL MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080279821-A1 | ARYLPIPERIDINYL AND ARYLPYRROLIDINYL MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | PRSS1, CTSC, SPINT2 | CYP3A4 28/4885TSHR 4065/4885MEN1 4649/4885 |
| US-20230270750-A1 | CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS | BCHE, ACHE, CHAT | CYP3A4 157/4885TSHR 2545/4885MEN1 3307/4885 |
| US-20080317712-A1 | ARYLPIPERIDINYL AND ARYLPYRROLIDINYL TRIPEPTIDE HEPATITIS C SERINE PROTEASE INHIBITORS | PREP, DNPEP, CTSC | CYP3A4 74/4885TSHR 3955/4885MEN1 4697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.