Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL7760658 | 0.91 | HSD17B10 (0.40) | SMN1; SMN2HTTLMNAPKMPOLB | |
| Dimethylamine SCHEMBL7759251 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTLMNAPKMPOLB | |
| SCHEMBL9400406 | 0.88 | KCNK3 (0.42) | SMN1; SMN2HTTLMNAPKMHDAC8 | |
| SCHEMBL7760648 | 0.85 | CNR2 (0.43) | SMN1; SMN2LMNAALDH1A1MAPTRAB9A | |
| Dimethylamine SCHEMBL9400427 | 0.81 | MEN1 (0.39) | SMN1; SMN2HTTLMNAPOLBHDAC8 | |
| Diethylamine SCHEMBL7759226 | 0.80 | HSD17B10 (0.34) | HTTLMNAPKMPOLBHDAC8 | |
| Diethylamine SCHEMBL7760670 | 0.79 | HSD17B10 (0.35) | SMN1; SMN2HTTLMNAPKMPOLB | |
| Diethylamine SCHEMBL7761090 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTLMNAPKMPOLB | |
| Diethylamine SCHEMBL7759284 | 0.77 | GRM5 (0.38) | HTTLMNAPOLBHDAC8HDAC6 | |
| SCHEMBL7759250 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2HTTLMNAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5372917-A | Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1994-12-13 | — | — | US | disclosed |