SCHEMBL7760826

SCHEMBL7760826

C=C(C=C(C)C(=O)O)C(=O)OCC(CC)CCCC.C=C(CC=Cc1ccccc1)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.42
ALDH1A1 P00352 5/20 0.41
LMNA P02545 5/20 0.41
MAPK1 P28482 3/20 0.41
CYP3A4 P08684 3/20 0.41
CA2 P00918 1/20 0.41
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
TSHR P16473 4/20 0.36
HSD17B10 Q99714 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
PAM P19021 1/20 0.32
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10867479 0.86 KDM4E (0.45) TDP1ALDH1A1LMNATSHRKDM4E
SCHEMBL5952121 0.86 TDP1 (0.44) TDP1ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL11280617 0.86 ALDH1A1 (0.52) TDP1ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL2352029 0.84 TSHR (0.56) TDP1ALDH1A1LMNAMAPK1CYP3A4
Styrene SCHEMBL3297409 0.84 ALDH1A1 (0.48) TDP1ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL8412096 0.84 ALDH1A1 (0.42) ALDH1A1LMNAKDM4EPAMMAOB
SCHEMBL2246656 0.83 ALDH1A1 (0.47) TDP1ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL2297800 0.82 LMNA (0.39) TDP1ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL10940136 0.81 KDM4E (0.42) TDP1ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL2893858 0.81 TSHR (0.47) TDP1ALDH1A1LMNAMAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770910-B1 Image forming method FUJI PHOTO FILM CO LTD (JP) 2001-05-16 EP disclosed
US-5736293-A USING MIXTURES OF 1-PHENYL-3-PYRAZOLIDONES AND CATECHOLS(AND DERIVATIVES) AS REDUCING AGENTS IN HEAT DEVELOPMENT OF A LAMINATED PHOTOSENSITIVE SHEET YIELDS HIGH DENSITY IMAGES HAVING LOW FOGGING, GOOD HALFTONES AND HIGH CONTRAST FUJI PHOTO FILM CO., LTD. (JP) 1998-04-07 US disclosed
EP-0770910-A1 Image forming method FUJI PHOTO FILM CO., LTD. (JP) 1997-05-02 EP disclosed