SCHEMBL7760865

SCHEMBL7760865

Cc1ccc(C2C=Cc3ccccc32)c(C2C=Cc3ccccc32)c1C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.32
HTR6 P50406 1/20 0.31
HTR2A P28223 1/20 0.31
CYP1A2 P05177 1/20 0.30
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6055955 0.84 HTR2C (0.40) SIGMAR1HTR6HTR2AHTR2C
SCHEMBL2959833 0.84 ALDH1A1 (0.31)
SCHEMBL2969302 0.82 SIGMAR1 (0.31) SIGMAR1HTR6HTR2A
SCHEMBL2957717 0.79 SIGMAR1 (0.31) SIGMAR1HTR6HTR2A
SCHEMBL2830663 0.78 HTR2C (0.37) SIGMAR1HTR6HTR2AHTR2C
SCHEMBL2958995 0.78 ALDH1A1 (0.31)
SCHEMBL2962881 0.77 HTR6 (0.31) HTR6HTR2A
SCHEMBL2962850 0.76 CYP1A2 (0.32) CYP1A2
SCHEMBL8601261 0.74 CYP1A2 (0.42) CYP1A2
SCHEMBL2970857 0.74 CYP1A2 (0.37) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0752428-B1 Metallocene catalyst for the (co)polimerization of alpha-olefins ENICHEM SPA (IT) 2001-04-04 EP disclosed
US-5753578-A ADDITION POLYMERIZATION CATALYSTS CONTAINING A CO-CATALYST ENICHEM S.P.A. (IT) 1998-05-19 US disclosed
EP-0752428-A2 Metallocene catalyst for the (co)polimerization of alpha-olefins ENICHEM S.p.A. (IT) 1997-01-08 EP disclosed