Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29605577 | 0.81 | MAPT (0.38) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL394140 | 0.81 | MAPT (0.38) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31323968 | 0.77 | ALDH1A1 (0.38) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6600450 | 0.75 | NOS3 (0.35) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23178711 | 0.73 | ALDH1A1 (0.41) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7812537 | 0.71 | TAAR1 (0.35) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6706335 | 0.71 | TAAR1 (0.63) | TAAR1 | |
| SCHEMBL84221 | 0.71 | TAAR1 (0.43) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6602644 | 0.71 | NPSR1 (0.38) | MAPTALDH1A1RAB9ASLC6A2SLC6A4 | |
| SCHEMBL6254533 | 0.71 | NOS3 (0.38) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740661-B1 | DIPHENYL OXAZOLINE DERIVATIVES | BAYER AG (DE) | 2001-04-18 | — | — | EP | disclosed |
| US-6051589-A | USED AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-18 | — | — | US | disclosed |
| EP-0831704-A1 | USE OF OXAZOLINES FOR COMBATTING ECTOPARASITES | BAYER AG (DE) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041534-A1 | USE OF OXAZOLINES FOR COMBATTING ECTOPARASITES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-27 | — | — | WO | disclosed |
| CN-1138854-A | Diphenyl oxazoline derivatives | BAYER AG (DE) | 1996-12-25 | — | — | CN | disclosed |
| EP-0740661-A1 | DIPHENYL OXAZOLINE DERIVATIVES | BAYER AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019350-A1 | DIPHENYL OXAZOLINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-20 | — | — | WO | disclosed |