SCHEMBL7761149

SCHEMBL7761149

CCCC(=O)c1ccccc1C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.47
MEN1 O00255 1/20 0.47
NR1I2 O75469 1/20 0.47
CHRM2 P08172 1/20 0.47
CYP3A4 P08684 1/20 0.47
ADRA2A P08913 1/20 0.47
OPRK1 P41145 1/20 0.47
HTR2B P41595 1/20 0.47
SLC6A3 Q01959 1/20 0.47
KMT2A Q03164 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HPGD P15428 4/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 5/20 0.47
HSD17B10 Q99714 3/20 0.47
KDM4E B2RXH2 3/20 0.47
TSHR P16473 2/20 0.47
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29291671 0.89 MAPT (0.53) LMNAMAPTMEN1NR1I2CHRM2
SCHEMBL28528492 0.85 MAPT (0.58) LMNAMAPTMEN1NR1I2CHRM2
Butyric Acid SCHEMBL27343834 0.84 FFAR3 (0.52) LMNAMAPTMEN1NR1I2CHRM2
SCHEMBL7833654 0.83 ALDH1A1 (0.50) LMNAMAPTMEN1NR1I2CHRM2
SCHEMBL28429668 0.83 ALDH1A1 (0.42) LMNAMAPTMEN1NR1I2CHRM2
SCHEMBL28494378 0.83 ALDH1A1 (0.42) LMNAMAPTMEN1NR1I2CHRM2
SCHEMBL22123487 0.83 ALDH1A1 (0.42) LMNAMAPTMEN1NR1I2CHRM2
SCHEMBL10229644 0.82 LMNA (0.50) LMNAMAPTMEN1CYP3A4KMT2A
SCHEMBL9533934 0.82 ALDH1A1 (0.58) LMNAMEN1KMT2AHPGDSMN1; SMN2
Alcohol SCHEMBL8861714 0.81 KDM4E (0.56) LMNAMAPTMEN1NR1I2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115666501-A Skin care product with protein matrix 第八日实验室有限责任公司 2023-01-31 CN disclosed
CN-111631989-B Anti-wrinkle composition and preparation method and application thereof 泉后(广州)生物科技研究院有限公司 2022-10-11 CN disclosed
CN-112022751-A Tightening lifting mask 惠州市好好爱日化用品有限公司 2020-12-04 CN disclosed
EP-1104404-A1 SUBSTITUTED ISOQUINOLINE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS SMITHKLINE BEECHAM PLC (GB) 2001-06-06 EP disclosed
WO-2000009486-A1 SUBSTITUTED ISOQUINOLINE DERIVATIVES AND THEIR USE AS ANTICONVULSIVANTS SMITHKLINE BEECHAM P.L.C. (GB) 2000-02-24 WO disclosed