Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932617 | 0.88 | KDM4E (0.58) | ALDH1A1ALOX15HPGDL3MBTL1KDM4E | |
| SCHEMBL29619308 | 0.88 | KDM4E (0.58) | ALDH1A1ALOX15HPGDL3MBTL1KDM4E | |
| SCHEMBL5440917 | 0.88 | KDM4E (0.58) | ALDH1A1ALOX15HPGDL3MBTL1KDM4E | |
| SCHEMBL5444639 | 0.86 | KDM4E (0.57) | ALDH1A1ALOX15HPGDL3MBTL1KDM4E | |
| SCHEMBL5444333 | 0.86 | KDM4E (0.57) | ALDH1A1ALOX15HPGDL3MBTL1KDM4E | |
| SCHEMBL5436833 | 0.86 | KDM4E (0.57) | ALDH1A1ALOX15HPGDL3MBTL1KDM4E | |
| SCHEMBL5438876 | 0.86 | KDM4E (0.57) | ALDH1A1ALOX15HPGDL3MBTL1KDM4E | |
| SCHEMBL9625496 | 0.86 | MEN1 (0.53) | ALDH1A1ALOX15KDM4ERECQLMEN1 | |
| SCHEMBL5436539 | 0.86 | KDM4E (0.57) | ALDH1A1ALOX15HPGDL3MBTL1KDM4E | |
| Phthalic Acid SCHEMBL8155 | 0.85 | ALDH1A1 (0.61) | ALDH1A1ALOX15HPGDSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108623456-B | Preparation method of butylphthalide and pharmaceutical intermediate thereof | 齐鲁制药有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-118393015-A | Detection method of butylphthalide related substances | 广东隆赋药业股份有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-116874453-A | Butylphthalide impurity compound, preparation method and application thereof | 广东隆赋药业股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-108623456-B | Preparation method of butylphthalide and pharmaceutical intermediate thereof | 齐鲁制药有限公司 | 2021-12-31 | — | — | CN | disclosed |
| WO-2020163673-A1 | INHIBITORS OF ADENYLATE-FORMING ENZYME MENE | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-08-13 | — | — | WO | disclosed |
| US-20170112843-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | THE SCRIPPS RESEARCH INSTITUTE | 2017-04-27 | — | — | US | disclosed |
| US-9464065-B2 | Compounds and methods for inducing chondrogenesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-10-11 | — | — | US | disclosed |
| EP-0575425-A1 | USE OF OXAZOLO- 2,3-a]ISOINDOLE AND IMIDAZO 2,1-a]ISOINDOLE DERIVATIVES AS ANTIVIRAL DRUGS, AND NEW OXAZOLO 2,3-a]ISOINDOLE DERIVATIVES. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-12-29 | — | — | EP | disclosed |
| WO-1992016207-A1 | USE OF OXAZOLO-[2,3-a]ISOINDOLE AND IMIDAZO[2,1-a]ISOINDOLE DERIVATIVES AS ANTIVIRAL DRUGS, AND NEW OXAZOLO[2,3-a]ISOINDOLE DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |
| US-4058529-A | Polycyclic amino derivatives of pyrrolidone and piperidone | CIBA-GEIGY CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170112843-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | COL2A1, BMP4, BMP2 | ALDH1A1 63/4885ALOX15 663/4885HPGD 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.