Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 11/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL513339 | 0.94 | MAPT (0.42) | AURKATPX2KIF11NISCHPIM1 | |
| Tetrahydrofuran SCHEMBL16564614 | 0.80 | PIM1 (0.38) | NISCHPIM1PIM2MAPTEPHX2 | |
| SCHEMBL27219430 | 0.78 | PIM1 (0.30) | PIM1PIM2 | |
| SCHEMBL4150750 | 0.77 | KIF11 (0.49) | AURKATPX2KIF11SCN5ANISCH | |
| SCHEMBL9013501 | 0.76 | MAPT (0.45) | KIF11NISCHPIM1PIM2NOTUM | |
| SCHEMBL254957 | 0.75 | MAPT (0.56) | KIF11NISCHPIM1PIM2NOTUM | |
| SCHEMBL7938385 | 0.74 | KIF11 (0.50) | AURKATPX2KIF11SCN5ANISCH | |
| SCHEMBL306823 | 0.74 | KIF11 (0.50) | AURKATPX2KIF11SCN5ANISCH | |
| SCHEMBL18293362 | 0.74 | KIF11 (0.50) | AURKATPX2KIF11SCN5ANISCH | |
| Bromide SCHEMBL9250086 | 0.74 | MAPT (0.44) | KIF11NISCHPIM1PIM2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711777-B1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHINETSU CHEMICAL CO (JP) | 2001-04-04 | — | — | EP | disclosed |