SCHEMBL513339

SCHEMBL513339

FC(F)(F)Oc1ccc([Mg]Br)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.42
▸ EPHX2 P34913 1/20 0.42
▸ PIM1 P11309 1/20 0.42
▸ PIM2 Q9P1W9 1/20 0.42
▸ ALDH1A1 P00352 2/20 0.40
▸ MAOB P27338 1/20 0.40
▸ AOC3 Q16853 1/20 0.40
▸ GPR3 P46089 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ NOS3 P29474 2/20 0.38
▸ NOS1 P29475 2/20 0.38
▸ NOS2 P35228 2/20 0.38
▸ AURKA O14965 1/20 0.38
▸ TPX2 Q9ULW0 1/20 0.38
▸ KIF11 P52732 1/20 0.37
▸ CES1 P23141 1/20 0.37
▸ PDE2A O00408 1/20 0.37
▸ NISCH Q9Y2I1 1/20 0.37
▸ TSHR P16473 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7761174 0.94 AURKA (0.45) MAPTEPHX2PIM1PIM2AURKA
SCHEMBL27219430 0.83 PIM1 (0.30) PIM1PIM2
SCHEMBL9013501 0.81 MAPT (0.45) MAPTEPHX2PIM1PIM2ALDH1A1
SCHEMBL254957 0.80 MAPT (0.56) MAPTEPHX2PIM1PIM2ALDH1A1
Bromide SCHEMBL9250086 0.79 MAPT (0.44) MAPTEPHX2PIM1PIM2ALDH1A1
SCHEMBL661716 0.77 SLC6A2 (0.35) MAPTKDM4EKIF11KMT2AMEN1
SCHEMBL624234 0.75 CETP (0.41) MAPTPIM1PIM2ALDH1A1GPR3
SCHEMBL31308775 0.75 CETP (0.41) MAPTPIM1PIM2ALDH1A1GPR3
SCHEMBL362085 0.74 ALDH1A1 (0.45) MAPTEPHX2ALDH1A1MAOBAOC3
SCHEMBL220074 0.73 MAPT (0.47) MAPTEPHX2ALDH1A1MAOBAOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242747-A1 MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS MERCK PATENT GMBH (DE) 2025-11-27 — — WO claimed
EP-0779885-A1 ANTIVIRAL NUCLEOSIDE ANALOGUES CONTAINING A SUBSTITUTED BENZIMIDAZOLE BASE ATTACHED TO A CARBOCYCLIC RING THE WELLCOME FOUNDATION LIMITED (GB) 1997-06-25 — — EP claimed
WO-1996007646-A1 ANTIVIRAL NUCLEOSIDE ANALOGUES CONTAINING A SUBSTITUTED BENZIMIDAZOLE BASE ATTACHED TO A CARBOCYCLIC RING THE WELLCOME FOUNDATION LIMITED (GB) 1996-03-14 — — WO claimed
US-12606533-B2 3-phenylpropylamine derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2026-04-21 — — US disclosed
US-12568969-B2 Pyridine compounds for controlling invertebrate pests FMC CORPORATION (US) 2026-03-10 — — US disclosed
US-20250388585-A1 PRMT5 INHIBITORS AND USES THEREOF GILEAD SCIENCES INC (US) 2025-12-25 — — US disclosed
WO-2025242747-A1 MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS MERCK PATENT GMBH (DE) 2025-11-27 — — WO disclosed
US-20250353824-A1 3-PHENYLPROPYLAMINE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-11-20 — — US disclosed
EP-4143179-B1 AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS FOR THE TREATMENT OF CANCER IDORSIA PHARMACEUTICALS LTD (CH) 2025-10-22 — — EP disclosed
US-12448388-B2 PRMT5 inhibitors and uses thereof GILEAD SCIENCES, INC. (US) 2025-10-21 — — US disclosed
EP-4021901-B1 SUBSTITUTED PYRIDOPYRIMIDINONYL COMPOUNDS USEFUL AS T CELL ACTIVATORS BRISTOL MYERS SQUIBB CO (US) 2025-09-24 — — EP disclosed
US-5639763-A FOR AGRICULTURAL APPLICATIONS FMC CORPORATION (US) 1997-06-17 — — US disclosed
CN-1147193-A Insecticidal N-(substd. Arylmethyl)-4-[bis(substd. phenyl) methyl] piperidines FMC CORP (US) 1997-04-09 — — CN disclosed
EP-0748159-A1 INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL)METHYL]PIPERIDINES FMC CORPORATION (US) 1996-12-18 — — EP disclosed
EP-0568040-B1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORP (JP) 1996-12-04 — — EP disclosed
WO-1996036228-A1 INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4-[BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES FMC CORPORATION (US) 1996-11-21 — — WO disclosed
US-5569664-A AGRICULTURAL INSECTICIDES FMC CORPORATION (US) 1996-10-29 — — US disclosed
US-5468421-A Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1995-11-21 — — US disclosed
WO-1995023507-A1 INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4-[BIS(SUBSTITUTED PHENYL)METHYL]PIPERIDINES FMC CORPORATION (US) 1995-09-08 — — WO disclosed
EP-0568040-A1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1993-11-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388585-A1 PRMT5 INHIBITORS AND USES THEREOF PRMT1, PRMT5, PRMT6 MAPT 3947/4885EPHX2 3141/4885PIM1 809/4885
US-20250353824-A1 3-PHENYLPROPYLAMINE DERIVATIVE SF1, SF3A1, SFXN1 MAPT 2719/4885EPHX2 2821/4885PIM1 1216/4885
US-12448388-B2 PRMT5 inhibitors and uses thereof PRMT5, PRMT1, PRMT9 MAPT 2217/4885EPHX2 2763/4885PIM1 396/4885
US-12568969-B2 Pyridine compounds for controlling invertebrate pests COX6C, CCR1, CBR3 MAPT 4823/4885EPHX2 1029/4885PIM1 4031/4885
US-12606533-B2 3-phenylpropylamine derivative SF3A1, SF1, HTR1D MAPT 4210/4885EPHX2 2146/4885PIM1 2324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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