Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8276259 | 0.84 | ABCB1 (0.56) | ABCB1ALDH1A1MAPTHPGDCTSL | |
| SCHEMBL5149951 | 0.79 | ABCB1 (0.58) | ABCB1ALDH1A1MAPTHPGDCTSL | |
| SCHEMBL14304888 | 0.78 | ABCB1 (0.51) | ABCB1ALDH1A1MAPTHPGDCTSL | |
| SCHEMBL567436 | 0.78 | ABCB1 (0.51) | ABCB1ALDH1A1MAPTHPGDCTSL | |
| SCHEMBL25100442 | 0.78 | ABCB1 (0.53) | ABCB1ALDH1A1MAPTHPGDCTSL | |
| SCHEMBL1460239 | 0.78 | ABCB1 (0.53) | ABCB1ALDH1A1MAPTHPGDCTSL | |
| SCHEMBL8697935 | 0.78 | ABCB1 (0.53) | ABCB1ALDH1A1MAPTHPGDCTSL | |
| SCHEMBL381080 | 0.78 | ABCB1 (0.53) | ABCB1ALDH1A1MAPTHPGDCTSL | |
| SCHEMBL22402324 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL381082 | 0.78 | ABCB1 (0.53) | ABCB1ALDH1A1MAPTHPGDCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100762-A2 | ERYTHROMYCIN DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006606-A2 | ERYTHROMYCIN DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 2000-02-10 | — | — | WO | disclosed |