Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756740 | 0.87 | CHRM2 (0.44) | CHRM2CA12CA1CA2CA9 | |
| SCHEMBL7761424 | 0.86 | SIGMAR1 (0.46) | CHRM2GAAMEN1KMT2ABCHE | |
| SCHEMBL7760542 | 0.82 | SCN8A (0.41) | SCN8A | |
| SCHEMBL9685732 | 0.80 | LTA4H (0.42) | ALDH1A1KDM4ESLC2A1 | |
| SCHEMBL7756742 | 0.78 | CHRM2 (0.48) | CHRM2SCN8ACA12CA1CA2 | |
| SCHEMBL9685789 | 0.75 | SKP2 (0.41) | CA1CA2ALDH1A1DRD2DRD3 | |
| SCHEMBL8798735 | 0.75 | PDE3B (0.41) | CA12CA1CA2CA4CA9 | |
| SCHEMBL8114298 | 0.72 | HRH1 (0.37) | HTR2A | |
| SCHEMBL22839742 | 0.70 | CHRM2 (0.92) | CHRM2SCN8ACA12CA1CA2 | |
| SCHEMBL2930997 | 0.70 | CHRM2 (0.85) | CHRM2SCN8ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | disclosed |
| CN-1050601-C | Preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 2000-03-22 | — | — | CN | disclosed |
| CN-1111626-A | Preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 1995-11-15 | — | — | CN | disclosed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |