Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.34 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.34 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204489 | 0.84 | KDM4E (0.34) | NISCHSMN1; SMN2HPGDCYP1A2ALDH1A1 | |
| SCHEMBL8114298 | 0.84 | HRH1 (0.37) | CYP2D6CYP1A2CYP2C19SIGMAR1 | |
| SCHEMBL6541584 | 0.84 | SKP2 (0.37) | SKP2HTR1DCA2CYP3A4HTR1A | |
| SCHEMBL9437760 | 0.83 | L3MBTL1 (0.41) | SMN1; SMN2HPGDMAPK1NPSR1CYP1A2 | |
| SCHEMBL7756751 | 0.78 | SIGMAR1 (0.44) | SIGMAR1DRD2 | |
| SCHEMBL7765516 | 0.78 | RECQL (0.31) | — | |
| SCHEMBL27450752 | 0.73 | SLC6A2 (0.32) | HTR1A | |
| SCHEMBL9484633 | 0.73 | HSD17B3 (0.44) | CA2HPGD | |
| SCHEMBL9449426 | 0.73 | SIGMAR1 (0.57) | HTR1ASIGMAR1DRD2 | |
| SCHEMBL9685609 | 0.70 | DRD2 (0.39) | SKP2SMN1; SMN2CA2HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |