SCHEMBL7761900

SCHEMBL7761900

CCOC(=O)C1OC1C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 3/20 0.59
TSHR P16473 1/20 0.47
CTSL P07711 3/20 0.47
CTSB P07858 2/20 0.47
LMNA P02545 1/20 0.47
CTSG P08311 1/20 0.47
POLB P06746 1/20 0.43
MMP1 P03956 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
FCER2 P06734 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7406064 0.91 CAPN1 (0.61) CAPN1TSHRCTSLCTSBLMNA
SCHEMBL11667610 0.91 CAPN1 (0.61) CAPN1TSHRCTSLCTSBLMNA
SCHEMBL9229815 0.87 CAPN1 (0.58) CAPN1TSHRCTSLCTSBLMNA
SCHEMBL7202933 0.87 CAPN1 (0.64) CAPN1TSHRCTSLCTSBLMNA
SCHEMBL7765666 0.85 CAPN1 (0.59) CAPN1CTSLCTSBLMNACTSG
SCHEMBL7763979 0.85 CAPN1 (0.77) CAPN1CTSLCTSBLMNACTSG
SCHEMBL7761860 0.84 CAPN1 (0.58) CAPN1CTSLCTSBLMNACTSG
SCHEMBL7765729 0.84 CAPN1 (0.52) CAPN1CTSBMMP1FCER2
SCHEMBL6070379 0.84 CAPN1 (0.52) CAPN1CTSBMMP1FCER2
SCHEMBL7765736 0.84 CAPN1 (0.52) CAPN1CTSBMMP1FCER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808839-B1 EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME TAIHO PHARMACEUTICAL CO LTD (JP) 2001-05-23 EP disclosed
EP-0808839-A1 EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME TAIHO PHARMACEUTICAL CO., LTD. (JP) 1997-11-26 EP disclosed