Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.64 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 6/20 | 0.47 |
| ▸ | FCER2 | P06734 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 9/20 | 0.45 |
| ▸ | MMP3 | P08254 | 4/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763979 | 0.91 | CAPN1 (0.77) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7406064 | 0.90 | CAPN1 (0.61) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL11667610 | 0.90 | CAPN1 (0.61) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7765666 | 0.89 | CAPN1 (0.59) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7761860 | 0.88 | CAPN1 (0.58) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7761900 | 0.87 | CAPN1 (0.59) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7762766 | 0.87 | CTSL (0.60) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7765662 | 0.87 | CTSL (0.60) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL9229815 | 0.86 | CAPN1 (0.58) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7209529 | 0.86 | CAPN1 (0.59) | CAPN1MMP1FCER2MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921122-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6110967-A | USEFUL AS AGENTS FOR PREVENTING AND TREATING METABOLIC OSTEOPATHY SUCH AS OSTEOPOROSIS, HYPERCALCEMIA AND BONE METASTASIS OF CANCER BECAUSE THEY SPECIFICALLY INHIBITS CATHEPSIN L AND ITS FAMILY ENZYMES TO INHIBIT BONE RESORPTION | TAIHO PHARMACEUTICALS CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0921122-A1 | NOVEL EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-06-09 | — | — | EP | disclosed |