Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.59 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CTSG | P08311 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | FCER2 | P06734 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761860 | 0.90 | CAPN1 (0.58) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7765662 | 0.89 | CTSL (0.60) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7762766 | 0.89 | CTSL (0.60) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7202933 | 0.89 | CAPN1 (0.64) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7402596 | 0.88 | CAPN1 (0.55) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL9088985 | 0.88 | CAPN1 (0.57) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL11667610 | 0.88 | CAPN1 (0.61) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7406064 | 0.88 | CAPN1 (0.61) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7763979 | 0.87 | CAPN1 (0.77) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL9088881 | 0.87 | CAPN1 (0.54) | CAPN1CTSLCTSBLMNACTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |