SCHEMBL7761965

SCHEMBL7761965

Nc1ccc(C(=O)O)c(CCC(O)O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.49
ALDH1A1 P00352 5/20 0.49
KDM4E B2RXH2 5/20 0.49
CYP3A4 P08684 3/20 0.49
GAA P10253 1/20 0.49
ESR2 Q92731 1/20 0.49
PTPN1 P18031 1/20 0.49
TDP1 Q9NUW8 4/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
THRB P10828 2/20 0.44
RECQL P46063 2/20 0.44
KDR P35968 2/20 0.44
POLB P06746 2/20 0.44
USP2 O75604 1/20 0.44
PKM P14618 1/20 0.44
APEX1 P27695 1/20 0.44
BLM P54132 1/20 0.44
MCL1 Q07820 1/20 0.44
TNF P01375 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28062236 0.86 ALDH1A1 (0.59) MAPTALDH1A1KDM4ECYP3A4GAA
SCHEMBL3897418 0.83 KDM4E (0.47) MAPTALDH1A1KDM4EGAAPTPN1
SCHEMBL29632107 0.82 ALDH1A1 (0.55) MAPTALDH1A1KDM4ECYP3A4GAA
SCHEMBL343331 0.82 ALDH1A1 (0.55) MAPTALDH1A1KDM4ECYP3A4GAA
SCHEMBL308882 0.82 ALDH1A1 (0.55) MAPTALDH1A1KDM4ECYP3A4GAA
SCHEMBL29632227 0.82 ALDH1A1 (0.55) MAPTALDH1A1KDM4ECYP3A4GAA
SCHEMBL17881330 0.81 ALDH1A1 (0.41) MAPTALDH1A1KDM4ECYP3A4GAA
SCHEMBL6024151 0.81 TSHR (0.41) MAPTALDH1A1KDM4ECYP3A4GAA
SCHEMBL30833194 0.81 MAPT (0.53) MAPTALDH1A1KDM4ECYP3A4GAA
SCHEMBL7100581 0.81 ALDH1A1 (0.53) MAPTALDH1A1KDM4ECYP3A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3188708-B1 MINERAL SUNSCREEN COMPOSITIONS EDGEWELL PERSONAL CARE BRANDS LLC (US) 2023-05-03 EP claimed
EP-3148507-B1 COSMETIC COMPOSITIONS WITH ENHANCED COLOR RETENTION FOR IMPROVED SKIN APPEARANCE EDGEWELL PERSONAL CARE BRANDS LLC (US) 2019-07-10 EP claimed
EP-2999521-B1 SYNERGISTIC PHOTOPROTECTIVE COMPOSITIONS EDGEWELL PERSONAL CARE BRANDS LLC (US) 2019-01-09 EP claimed
EP-3013313-B1 NON-IRRITATING, NON-WHITENING PHOTOPROTECTIVE COMPOSITIONS EDGEWELL PERSONAL CARE BRANDS LLC (US) 2018-12-26 EP claimed
EP-1155063-A1 EPOXY COMPOUNDS FOR DENTAL MEDICAL AND/OR DENTAL TECHNICAL APPLICATIONS LSP Dental Chemistry AG (CH) 2001-11-21 EP disclosed
EP-0920859-B1 Aqueous dispersion containing as UV-filter an organopolysiloxane functionalised with benzalmalonate and a water insoluble cationic tensid OREAL (FR) 2001-04-11 EP disclosed
WO-2000049064-A1 EPOXY COMPOUNDS FOR DENTAL MEDICAL AND/OR DENTAL TECHNICAL APPLICATIONS LSP DENTAL CHEMISTRY AG (CH) 2000-08-24 WO disclosed
EP-0920859-A1 Aqueous dispersion containing as UV-filter an organopolysiloxane functionalised with benzalmalonate and a water insoluble cationic tensid L'OREAL (FR) 1999-06-09 EP disclosed