Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.70 |
| ▸ | AR | P10275 | 3/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | SHBG | P04278 | 1/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.51 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623116 | 0.86 | PGR (0.75) | PGRARCHRM1CYP19A1MEN1 | |
| SCHEMBL7763543 | 0.85 | AR (0.72) | PGRARCHRM1CYP19A1MEN1 | |
| SCHEMBL5020044 | 0.83 | PGR (1.00) | PGRARCHRM1CYP19A1MEN1 | |
| SCHEMBL8942 | 0.83 | PGR (1.00) | PGRARCHRM1CYP19A1MEN1 | |
| SCHEMBL16690685 | 0.83 | PGR (1.00) | PGRARCHRM1CYP19A1MEN1 | |
| SCHEMBL2294866 | 0.83 | PGR (1.00) | PGRARCHRM1CYP19A1MEN1 | |
| Ethylene Glycol SCHEMBL28094936 | 0.81 | PGR (0.92) | PGRARCHRM1CYP19A1MEN1 | |
| Acetic Acid SCHEMBL25192781 | 0.81 | PGR (0.96) | PGRARCHRM1CYP19A1MEN1 | |
| Acetic Acid SCHEMBL28104035 | 0.80 | PGR (0.94) | PGRARCHRM1CYP19A1MEN1 | |
| Chlormadinone SCHEMBL13358512 | 0.80 | PGR (0.78) | PGRARCHRM1CYP19A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1094798-A2 | INHIBITORS OF TYPE 5 AND TYPE 3 17beta-HYDROXYSTEROID DEHYDROGENASE AND METHODS FOR THEIR USE | Endorecherche Inc. (CA) | 2001-05-02 | — | — | EP | disclosed |
| WO-1999046279-A2 | INHIBITORS OF TYPE 5 AND TYPE 3 17β-HYDROXYSTEROID DEHYDROGENASE AND METHODS FOR THEIR USE | ENDORECHERCHE, INC. (CA) | 1999-09-16 | — | — | WO | disclosed |