SCHEMBL7761992

SCHEMBL7761992

CNC(=O)C(NC(=O)OC(C)(C)C)C(C)(C)NC(=O)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.53
CTSS P25774 9/20 0.50
PPARA Q07869 2/20 0.50
CTSK P43235 6/20 0.48
CTSL P07711 5/20 0.48
CTSB P07858 3/20 0.48
MAPT P10636 1/20 0.47
PPARG P37231 1/20 0.45
ATM Q13315 1/20 0.45
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3002825 0.84 SYK (0.59) SYKCTSSPPARACTSKCTSL
SCHEMBL7763755 0.84 SYK (0.54) SYKCTSSPPARACTSKCTSL
SCHEMBL13244981 0.83 SYK (0.58) SYKCTSSPPARACTSKCTSL
SCHEMBL13337480 0.83 SYK (0.58) SYKCTSSPPARACTSKCTSL
SCHEMBL8649599 0.81 MMP2 (0.54) SYKCTSSCTSKCTSLCTSB
SCHEMBL8280590 0.81 MMP2 (0.54) SYKCTSSCTSKCTSLCTSB
SCHEMBL7308646 0.81 CTSS (0.53) SYKCTSSCTSKCTSLCTSB
SCHEMBL7763570 0.79 SYK (0.56) SYKCTSSPPARACTSKCTSL
SCHEMBL6241676 0.79 SYK (0.61) SYKCTSSPPARACTSKCTSL
SCHEMBL7763565 0.79 SYK (0.56) SYKCTSSPPARACTSKCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1101492-A1 NOVEL REMEDIES FOR ALLERGIC DISEASES FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 2001-05-23 EP disclosed
EP-1038864-A1 NOVEL METALLOPROTEINASE INHIBITORS FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 2000-09-27 EP disclosed