Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13159623 | 0.82 | IDO1 (0.44) | KMT2AGAAPOLBTHRBALOX12 | |
| SCHEMBL6404409 | 0.81 | KDM4E (0.49) | KMT2AGAAPOLBTHRBALOX12 | |
| SCHEMBL13159633 | 0.78 | POLB (0.45) | KMT2AGAAPOLBTHRBALOX12 | |
| SCHEMBL29922790 | 0.77 | MAPT (0.41) | KMT2AGAATHRBMAPTHTT | |
| SCHEMBL21799639 | 0.77 | MAPT (0.41) | KMT2AGAATHRBMAPTHTT | |
| SCHEMBL10408184 | 0.77 | L3MBTL1 (0.49) | KMT2AGAAPOLBTHRBALOX12 | |
| SCHEMBL13602479 | 0.74 | CA12 (0.61) | KMT2AGAAMAPTALDH1A1TDP1 | |
| SCHEMBL10116969 | 0.74 | KMT2A (0.55) | KMT2APOLBMAPTSIGMAR1ALDH1A1 | |
| SCHEMBL20699481 | 0.73 | THRB (0.61) | KMT2AGAAPOLBTHRBALOX12 | |
| SCHEMBL15250784 | 0.73 | KMT2A (0.47) | KMT2AGAAPOLBTHRBALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512006-B1 | Novel 3-position Nitrogen substituted 6,6- disubstituted-5, 6-dihydropyrones and related compounds possess antiviral properties | WARNER-LAMBERT COMPANY | 2003-01-28 | — | — | US | disclosed |