Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936875 | 0.87 | ALDH1A1 (0.34) | PPARGPPARAALDH1A1CYP3A4 | |
| SCHEMBL7207646 | 0.74 | ALDH1A1 (0.38) | PPARGALDH1A1CYP3A4 | |
| SCHEMBL2362135 | 0.65 | CA5A (0.44) | ALDH1A1 | |
| SCHEMBL5704708 | 0.65 | PPARG (0.34) | PPARGPPARA | |
| SCHEMBL6942637 | 0.64 | PPARG (0.33) | PPARGPPARA | |
| SCHEMBL18242176 | 0.62 | PTPN1 (0.33) | ALDH1A1CYP3A4 | |
| SCHEMBL5704698 | 0.61 | — | — | |
| SCHEMBL18242211 | 0.61 | PTPN1 (0.32) | ALDH1A1CYP3A4 | |
| SCHEMBL18242227 | 0.60 | PTPN1 (0.31) | — | |
| SCHEMBL18242068 | 0.60 | PTPN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098662-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004892-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2000-02-03 | — | — | WO | disclosed |